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Luminescent terbium(III) probes containing aromatic amino acid-based antenna for discrimination between adenine and guanine nucleotides
Chemical Communications ( IF 4.3 ) Pub Date : 2024-12-20 , DOI: 10.1039/d4cc05232c
Sunanda Pradhan, NITIN SHUKLA, Goutam Panigrahi, Ashis Kumar Patra

Herein we present a series of luminescent Tb(III)-probes ([Tb-Ltrp], [Tb-Ltyr], [Tb-Lphe]) for sensing and discriminating purine nucleoside polyphosphates (NPP) based on a modified DTTA chelator appended to aromatic amino acids (Laa). The optically most effective luminescent [Tb-Ltrp] probe preferentially discriminate the guanine-NPPs over the adenine-NPPs via PeT-based modulation of Tb(III) luminescence within biological concentration range.
更新日期:2024-12-20
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