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FAS-less allogeneic CAR T cells
Nature Biomedical Engineering ( IF 26.8 ) Pub Date : 2024-12-20 , DOI: 10.1038/s41551-024-01319-y Keith P. Eidell, Michael T. Hemann
Nature Biomedical Engineering ( IF 26.8 ) Pub Date : 2024-12-20 , DOI: 10.1038/s41551-024-01319-y Keith P. Eidell, Michael T. Hemann
In immunocompetent hosts, the ablation of FAS and CD3 in allogeneic chimeric antigen receptor T cells confers them with partial protection from rejection by T cells and natural killer cells.
更新日期:2024-12-20