当前位置：
X-MOL 学术
›
Mol. Nutr. Food Res.
›
论文详情
Our official English website, www.x-mol.net, welcomes your
feedback! (Note: you will need to create a separate account there.)
The Neuroprotective Effect of Rooibos Herbal Tea Against Alzheimer's Disease: A Review
Molecular Nutrition & Food Research ( IF 4.5 ) Pub Date : 2024-12-20 , DOI: 10.1002/mnfr.202400670 Elias Chipofya, Taskeen F. Docrat, Jeanine L. Marnewick
Molecular Nutrition & Food Research ( IF 4.5 ) Pub Date : 2024-12-20 , DOI: 10.1002/mnfr.202400670 Elias Chipofya, Taskeen F. Docrat, Jeanine L. Marnewick
|
The world is experiencing a demographic shift toward an increasing proportion of elderly persons. Alzheimer's disease (AD) and other neurological disorders are far more likely to develop as people age. AD is a gradual, irreversible, and degenerative brain disorder that progressively deteriorates memory and cognitive function, eventually leading to death. Treatment for AD is the most significant unmet clinical need in neurology. There are no effective treatment options to prevent or reverse the degenerative process. The current medical management focuses primarily on temporarily easing symptoms, with little or no overall improvement. Although genetic predisposition and lifestyle factors influence the risk of neurodegenerative disorders, recent research suggests that dietary polyphenols with solid antioxidant capacities play crucial roles in determining brain health and aging. Aspalathus linearis is used to produce Rooibos, a popular South African herbal tea, which may modulate neurodegenerative mechanisms such as oxidative stress, tau protein, amyloid plaques, inflammation, and metals, all of which have been associated with AD. We reviewed the literature to evaluate the potential neuroprotective effects of Rooibos and its major flavonoids and to understand the underlying molecular mechanisms.
更新日期：2024-12-20
京公网安备 11010802027423号