In a recent issue of Nature Chemistry, Zhang and coworkers showed that the ATP-dependent N-nitrosylase Tri17 can catalyze azide synthesis. Tri17 is a promiscuous enzyme that can catalyze N-nitrosylation of various substrates. When specific substrates were used, it also catalyzed the dehydration of the N-nitroso moiety to synthesize an azide moiety.

中文翻译：

---

通过 ATP 依赖性合成酶进行酶促叠氮化物合成


在最近一期的《自然化学》杂志上，Zhang 及其同事表明，ATP 依赖性 N-亚硝基化酶 Tri17 可以催化叠氮化物合成。Tri17 是一种混杂酶，可以催化各种底物的 N-亚硝基化。当使用特定底物时，它还催化 N-亚硝基部分脱水以合成叠氮化物部分。