Nanoplastic particles (NPPs) have attracted lots of attention due to their toxicity. In this study, a Surface-enhanced Raman scattering (SERS)-based category on selectivity and quantification detecting the polystyrene (PS) NPPs has been presented. Firstly, the size-dependent SERS relationship between the diameter of Ag nanocavities (AgNCAs) and the diameter of the PS NPPs is studied. By continuously dripping the PS NPPs on proposed AgNCAs substrates, AgNCAs exhibit excellent enrichment capability with a promoted limit of detection (LOD) of 0.001 mg/mL. Secondly, thermally evaporated Ag nanoparticles (AgNPs) as an enhancement layer are used to form the AgNPs/PS NPPs/AgNCAs sandwich structure with a SERS enhancement of 300%. Thirdly, a SERS microfluidic chip constructed by integrating two kinds of pore size (87 nm and 356 nm) AgNCAs is fabricated to selectivity quantifying absolute concentration of the mixed PS NPPs with different diameters in a mixed solution. It shows excellent performance. This novel category proves a good method for identifying plastic nanoparticles and analyzing their size distribution existing in the surroundings indicating good practical applications.

中文翻译：

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使用高灵敏度的周期性 Ag 纳米腔 SERS 底物检测不同直径混合溶液中 PS 纳米塑料颗粒的尺寸依赖性选择性和定量


纳米塑料颗粒 （NPP） 因其毒性而引起广泛关注。在本研究中，提出了一种基于表面增强拉曼散射 （SERS） 的聚苯乙烯 （PS） NPP 选择性和定量检测类别。首先，研究了 Ag 纳米腔 （AgNCA） 直径与 PS NPP 直径之间的尺寸依赖性 SERS 关系。通过将 PS NPP 连续滴落在所提出的 AgNCAs 底物上，AgNCA 表现出优异的富集能力，提升的检测限 （LOD） 为 0.001 mg/mL。其次，使用热蒸发的 Ag 纳米颗粒 （AgNPs） 作为增强层形成 AgNPs/PS NPPs/AgNCAs 三明治结构，SERS 增强 300%。再次，通过集成两种孔径 （87nm 和 356nm） AgNCAs 构建 SERS 微流控芯片，以选择性量化混合溶液中不同直径的混合 PS NPPs 的绝对浓度。它显示出出色的性能。这种新颖的类别被证明是一种识别塑料纳米颗粒并分析它们在环境中存在的尺寸分布的好方法，表明具有良好的实际应用。