This paper introduces a novel approach to optimizing reactive distillation (RD) process before heat-integration (HI) to achieve greater energy savings in the subsequent heat-integrated configuration. While conventional approaches prioritize minimizing “overall energy consumption” before implementing HI, this study proposes minimizing the energy consumption of the RD column (RDC) first prior to HI to achieve more significant energy savings. Heat-integrated neat design RD and TCRD were investigated in this study. By comparing two scenarios, i.e., First scenario; minimizing overall energy consumption and Second scenario; minimizing the energy consumption of the RDC before HI, our findings demonstrated that the latter approach consistently achieves higher energy savings, ranging from 31.64% to 46.08% relative to the base case, following HI. Additionally, we observed that the hybrid heat-integrated configuration in our study has a higher energy consumption than the double-effect configuration. This was attributed to their shared dependence on RDC after HI. Altogether, our findings challenge conventional practices and offer an alternative pathway to enhance energy efficiency in industrial processes.

中文翻译：

---

一种设计热集成反应蒸馏工艺的新方法：应用于理想的间接整齐工艺案例


本文介绍了一种在热集成 （HI） 之前优化反应蒸馏 （RD） 工艺的新方法，以便在随后的热集成配置中实现更大的节能。虽然传统方法在实施 HI 之前优先考虑最小化“总能耗”，但本研究建议在 HI 之前先最小化 RD 塔 （RDC） 的能耗，以实现更显著的节能。本研究研究了热集成整洁设计 RD 和 TCRD。通过比较两种情况，即 第一种情况;最小化总体能耗和第二种情况;最小化 HI 之前 RDC 的能耗，我们的研究结果表明，后一种方法始终实现了更高的节能，相对于 HI 之后的基本情况，从 31.64% 到 46.08% 不等。此外，我们观察到，我们研究中的混合热集成配置比双效配置具有更高的能耗。这归因于他们在 HI 之后对 RDC 的共同依赖。总而言之，我们的研究结果挑战了传统做法，并为提高工业流程的能源效率提供了另一种途径。