INTRODUCTION Biopsy of hepatocellular carcinoma (HCC) may help with selecting appropriate chemotherapy with inconclusive imaging; concern about potential seeding may limit its use. METHODS A systematic review was conducted to assess the risk of tumor seeding with biopsy of HCC excluding nonliver cancers or seeding after interventions. RESULTS A total of 2,339 unique abstracts were identified; 37 studies were included in the final analysis. The rate of tumor seeding was 0.62% (range 0%-7.77%) in 13,959 biopsies performed. The average reported median lengths of follow-up was 35.8 months (range 10.5-60 months). DISCUSSION Overall, the risk of tumor seeding with biopsy of HCC is low.

中文翻译：

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肝细胞癌穿刺活检的肿瘤接种：系统评价。


引言 肝细胞癌 （HCC） 活检可能有助于选择合适的化疗，但影像学检查不确定;对潜在播种的担忧可能会限制其使用。方法 进行了一项系统评价，以评估 HCC 活检（不包括非肝癌）或干预后播种的肿瘤播散风险。结果 共确定 2,339 篇独特摘要;最终分析纳入了 37 项研究。在进行的 0.62 例活检中，肿瘤接种率为 7.77% （范围 13,959%）。报告的平均中位随访时间为 35.8 个月 （范围 10.5-60 个月）。讨论 总体而言，HCC 活检发生肿瘤播散的风险较低。