Thiamethoxam has been widely used in agriculture due to its excellent insecticidal activity. However, thiamethoxam is prone to loss during practical applications, especially in soil application, which seriously reduces its performance. In this work, thiamethoxam is loaded in ethyl cellulose microspheres to solve this issue, and the thiamethoxam-loaded ethyl cellulose microspheres (thiamethoxam/EC) are facilely and effectively fabricated by emulsified solvent volatilization. The exceptional embedding capacity of thiamethoxam/EC was elucidated through a systematic investigation of its controlled release and antiphotolysis properties. The encapsulation efficiency of thiamethoxam/EC was found to be ∼70.36%. Even after 130 h in a phosphate-buffered saline solution, the release of thiamethoxam from the thiamethoxam/EC complex continued, with a cumulative release of ∼52.38%. In contrast, the cumulative release of thiamethoxam/EC in soil after being flushed with 580 mL of water was a mere 14.74%, significantly lower than the value of 42.73% observed for unencapsulated thiamethoxam at the same volume. Additionally, thiamethoxam/EC demonstrated benign biocompatibility with Escherichia coli and maize (Zea mays L.) seedlings. The ultraviolet resistance of thiamethoxam in the thiamethoxam/EC formulation was nearly 3 times greater than that of uncoated thiamethoxam, and the insecticidal efficacy against Mythimna separata improved by 11.46% at a low concentration of 1 mg/L after a 10 day incubation in a greenhouse. The microspheroidization process not only extended the efficacy duration of fluazinam on target crops but also contributed to the sustainable use of pesticides and environmental protection.

中文翻译：

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载有噻虫嗪的乙基纤维素微球用于延长疗效持续时间和降低对玉米生长的毒性 （Zea mays L.）


噻虫嗪因其优异的杀虫活性而在农业上得到广泛应用。但噻虫嗪在实际应用中，特别是在土壤应用中容易损失，严重降低了其性能。在本工作中，将噻虫嗪负载在乙基纤维素微球中以解决这一问题，并通过乳化溶剂挥发轻松有效地制备了负载噻虫嗪的乙基纤维素微球 （thiamethoxam/EC）。通过对其控释和抗光解特性的系统研究，阐明了噻虫嗪/EC 的特殊包埋能力。发现噻虫嗪/EC 的包埋效率约为 ∼70.36%。即使在磷酸盐缓冲盐水溶液中 130 小时后，噻虫嗪/EC 复合物中噻虫嗪的释放仍在继续，累积释放量约为 52.38%。相比之下，用 580 mL 水冲洗后土壤中噻虫嗪/EC 的累积释放量仅为 14.74%，显著低于相同体积下未封装噻虫嗪观察到的 42.73% 的值。此外，噻虫嗪/EC 与大肠杆菌和玉米 （Zea mays L.） 幼苗具有良好的生物相容性。噻虫嗪/EC 制剂中噻虫嗪的紫外线抗性比未包衣的噻虫嗪高近 3 倍，在温室中培养 10 天后，在 1 mg/L 的低浓度下，对 Mythimna separata 的杀虫效果提高了 11.46%。微球化过程不仅延长了氟嗪南对目标作物的疗效持续时间，还有助于农药的可持续利用和环境保护。