The judicious selection and combination of multicomponents provide great potential for the further exploration of new polyoxometalate (POM) materials. Here, a delicate control on tungstate, Sb^III and Bi^III sources, Eu³⁺ ions, and organic molecules led to the discovery of a novel multimetal cluster-embedded POM [H₂N(CH₃)₂]₉Na₈H₅{[Eu₄(H₂O)₆Sb₄Bi₂W₂O₁₂](SbW₉O₃₃)₂(SbW₈O₃₁)₂}·78H₂O (1). The polyoxoanion of 1 was constructed from four in situ-formed [SbW₈O₃₁]^11– and [SbW₉O₃₃]^9– building blocks connected by two hexa-metallic [Eu₂(H₂O)₃Sb₂BiWO₆]⁹⁺ clusters, to be a rare member of Sb- and Bi-coexisting POM. The most impressive characteristic of 1 is the intricate [Eu₂(H₂O)₃Sb₂BiWO₆]⁹⁺ cluster linker, which contains a Sb^III–Bi^III coinserted [Sb₂BiWO₆]³⁺ core grasping one [Eu1(H₂O)₂]³⁺ cation and one [Eu2(H₂O)]³⁺ cation on both sides through Sb–O–Eu and Bi–O–Eu bonds. Functionalized by luminescence centers of Eu³⁺ ions, 1 can emit intense emission in water and be capable of detecting the biomarker of carcinoids, 5-hydroxyindoleacetic acid (5-HIAA) with a low limit of detection of 0.43 μM, high selectivity, and excellent anti-interference, as well as fast response (12 s). The high detectability of 1 for 5-HIAA is relevant to the underlying dynamic quenching and energy-transfer mechanism. In urine conditions, remarkable recognition of 1 for 5-HIAA and satisfactory recoveries were achieved, indicative of the possibility of 1 in detecting 5-HIAA in a real environment. This work reveals the special clustering effect of Sb^III and Bi^III atoms in the assembly of neoteric POM species and also promotes the application of POMs as potential diagnostic tool in the early detection of carcinoids.

中文翻译：

---

多核锑-铋-镧系元素簇连接的多金属氧酸盐，用于通过发光检测 5-羟基吲哚乙酸


多组分的明智选择和组合为进一步探索新的多金属氧酸盐 （POM） 材料提供了巨大的潜力。在这里，对钨酸盐、Sb^III 和 Bi^III 源、Eu³⁺ 离子和有机分子的精细控制导致了一种新型多金属团簇嵌入的 POM [H₂N（CH₃）₂]₉Na₈H₅{[Eu₄（H₂O）₆Sb₄Bi₂W_{2 O 12}]（SbW₉O₃₃）₂（SbW ₈O₃₁）₂}·78H₂O （1）.1 的多氧阴离子由四个原位形成的 [SbW₈O₃₁]^11– 和 [SbW₉O₃₃]^9– 构建单元构成，由两个六金属 [Eu₂（H₂O）₃Sb₂BiWO₆]⁹⁺ 簇连接，是 Sb 和双共存的 POM 的稀有成员。1 最令人印象深刻的特性是复杂的 [Eu₂（H₂O）₃Sb₂BiWO₆]⁹⁺ 簇连接子，其中包含一个 Sb^{III-Bi III} 共插入的 [Sb₂BiWO₆]³⁺ 核心，通过 Sb-O-Eu 和 Bi-O-Eu 键在两侧抓住一个 [Eu1（H₂O）₂]³⁺ 阳离子和一个 [Eu2（H₂O）]^]3+ 阳离子。 1 由 Eu³⁺ 离子的发光中心功能化，可在水中发射强发射，能够检测类癌的生物标志物 5-羟基吲哚乙酸 （5-HIAA），检测限低至 0.43 μM，选择性高，抗干扰性好，响应快 （12 s）。1 对 5-HIAA 的高可检测性与潜在的动态淬灭和能量传递机制有关。在尿液条件下，5-HIAA 对 1 的显着识别并取得了令人满意的回收率，表明 1 在真实环境中检测到 5-HIAA 的可能性。这项工作揭示了 Sb^III 和 Bi^III 原子在新生 POM 物种组装中的特殊聚集作用，也促进了 POMs 作为类癌早期检测的潜在诊断工具的应用。