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Low Skeletal Muscle Radiodensity Predicts Response to CDK4/6 Inhibitors Plus Aromatase Inhibitors in Advanced Breast Cancer
Journal of Cachexia, Sarcopenia and Muscle ( IF 9.4 ) Pub Date : 2024-12-17 , DOI: 10.1002/jcsm.13666
Hyunwook Kim, Seungjin Baek, Sookyeong Han, Gun Min Kim, Joohyuk Sohn, Yumie Rhee, Namki Hong, Min Hwan Kim

Recent evidence indicates that a dysregulated host metabolism influences treatment outcomes in patients with breast cancer. We investigated the association of computed tomography (CT)-derived body composition indices with therapeutic responses in patients with hormone receptor-positive, HER2-negative advanced breast cancer (ABC) on endocrine plus CDK4/6 inhibitor (CDK4/6i) treatment.

中文翻译:


低骨骼肌放射密度可预测晚期乳腺癌对 CDK4/6 抑制剂加芳香化酶抑制剂的反应



最近的证据表明,失调的宿主代谢会影响乳腺癌患者的治疗结果。我们研究了内分泌加 CDK4/6 抑制剂 (CDK4/6i) 治疗的激素受体阳性、HER2 阴性晚期乳腺癌 (ABC) 患者计算机断层扫描 (CT) 衍生的体成分指标与治疗反应的相关性。
更新日期:2024-12-17
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