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Synthesis and Biological Activity of 2,6-Disubstituted 7-Deazapurine Ribonucleosides
European Journal of Organic Chemistry ( IF 2.5 ) Pub Date : 2024-12-17 , DOI: 10.1002/ejoc.202401187
Ugnė Šinkevičiūtė, Marcela Dvořáková, Michal Tichý, Soňa Gurská, Kateřina Ječmeňová, Lenka Poštová Slavětínská, Petr Džubák, Marián Hajdúch, Michal Hocek

A series of 2,6-disubstituted derivatives of 7-deazapurine ribonucleosides with different combinations of aryl and arylalkynyl substituents were synthesized through regioselective cross-coupling reactions and tested for biological activity.

中文翻译:


2,6-二取代 7-脱氮嘌呤核糖核苷的合成及生物活性



通过区域选择叉偶联反应合成了一系列具有不同芳基和芳基炔基取代基组合的 7-脱氮嘌呤核糖核苷的 2,6-二取代衍生物,并进行了生物活性测试。
更新日期:2024-12-17
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