A strategy for synthesizing 4-amino-1,2,3-triazoles was established through sequential click cycloaddition and aminations mediated by triazolyl(Mes)iodonium salts. This method employs a copper-catalyzed process, characterized by mild conditions, a broad substrate scope, and straightforward operational procedures. The method facilitates the efficient construction of substituted aminotriazoles through both stepwise and one-pot syntheses. The practical synthesis of triazolyliodonium salts as stable solids is expected to enable further derivatizations.

中文翻译：

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通过点击环加成反应生成 4-氨基三唑类化合物和生成碘 （III） 三唑类化合物


通过连续点击环加成和三唑基（Mes）碘盐介导的胺化作用，建立了合成 4-氨基-1,2,3-三唑的策略。该方法采用铜催化工艺，其特点是条件温和、衬底范围广、操作程序简单。该方法有助于通过逐步和一锅法合成高效构建取代氨基三唑。三唑基碘盐作为稳定固体的实际合成有望实现进一步的衍生化。