A new strategy for the construction of chiral 4H‐chromene skeleton via Pd‐catalyzed asymmetric amination of 2H‐chromene was reported. A series of chiral 2‐trifluoromethyl‐4H‐chromenes containing 1,2,3,4‐tetrahydroquinoline unit were synthesized in moderate to good yields with excellent enantioselectivity, the method serves as an effective supplement to the construction of chiral 4H‐chromene skeleton.

中文翻译：

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通过 Pd 催化的不对称胺化反应合成手性 2-三氟甲基-4-（四氢喹啉基）-4H-铬烯


报道了一种通过 Pd 催化的 2H-铬的不对称胺化构建手性 4H-铬骨架的新策略。以中等至良好的产量合成了一系列含有 1,2,3,4-四氢喹啉单元的手性 2-三氟甲基-4H-铬烯，具有优异的对映选择性，该方法可作为构建手性 4H-铬骨架的有效补充。