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Efficient production of non-immunogenic, long circular RNAs for high protein yield
Nature Biomedical Engineering ( IF 26.8 ) Pub Date : 2024-12-17 , DOI: 10.1038/s41551-024-01307-2


Using trans-ribozyme-mediated circularization, we have produced circular RNAs that are not limited by RNA sequence or length and that allow for modifications. The synthesized RNAs increase protein expression more than 7,000-fold.

中文翻译:


高效生产非免疫原性长环 RNA,实现高蛋白产量



使用反式核酶介导的环化,我们产生了不受 RNA 序列或长度限制且允许修饰的环状 RNA。合成的 RNA 使蛋白质表达增加 7,000 倍以上。
更新日期:2024-12-17
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