GeroScience ( IF 5.3 ) Pub Date : 2024-12-17 , DOI: 10.1007/s11357-024-01446-z Chen Chen, Ning Huang, Ban Hu, Mingyu Zhang, Junliang Yuan, Jing Guo
Digital technology interventions (DTIs) are seen as promising interventions to prevent or delay cognitive decline in older adults, yet evidence from reviews is not conclusive. The aim of this study is to explore the effectiveness of DTIs in improving older adults’ cognitive function while taking study design and intervention characteristics as moderators. We searched the PubMed, Embase, CINAHL, PsycINFO, and Scopus databases up to May 26, 2023. Only randomized controlled trials examined the effects of DTIs on cognitive function were included in our study. Standardized mean difference (SMD) and 95% confidence interval for outcomes were applied in meta-analyses and subgroup analyses. A risk of bias assessment was also conducted. Overall, 23 eligible studies with a total sample size of 1454 participants were included. We found that DTIs significantly improved global cognitive function (SMD = 0.479), attention and processing speed (SMD = 0.488), executive function (SMD = 0.287), immediate recall (SMD = 0.266), and working memory (SMD = 0.307). Our subgroup analyses revealed that DTIs were more effective for cognitively impaired subjects, and DTIs with specific intervention characteristics, such as the inclusion of cognitive standard tasks, virtual reality-based interventions, specialized settings, professional guidance, low/medium-density training, > 24 sessions, and sessions lasting > 30 min, were more effective for different cognitive domains. This study supported the effectiveness of DTIs in improving cognitive function in older adults aged 60 years old and over, which may be influenced by study design and intervention characteristics. These findings have important implications for clinical dementia prevention and treatment strategies targeted at specific cognitive domains.
中文翻译:
数字技术干预对老年人认知功能的有效性:随机对照试验的系统评价和荟萃分析
数字技术干预 (DTI) 被视为预防或延缓老年人认知能力下降的有前途的干预措施,但综述中的证据尚无定论。本研究的目的是探讨 DTI 在改善老年人认知功能方面的有效性,同时以研究设计和干预特征为调节因素。我们检索了截至 2023 年 5 月 26 日的 PubMed、Embase、CINAHL、PsycINFO 和 Scopus 数据库。我们的研究仅纳入了检查 DTI 对认知功能影响的随机对照试验。在荟萃分析和亚组分析中应用结局的标准化均数差 (SMD) 和 95% 置信区间。还进行了偏倚风险评估。总体而言,共纳入了 23 项符合条件的研究,总样本量为 1454 名参与者。我们发现 DTI 显着改善了整体认知功能 (SMD = 0.479)、注意力和处理速度 (SMD = 0.488)、执行功能 (SMD = 0.287)、即时回忆 (SMD = 0.266) 和工作记忆 (SMD = 0.307)。我们的亚组分析显示,DTIs 对认知障碍受试者更有效,具有特定干预特征的 DTI,例如包含认知标准任务、基于虚拟现实的干预、专业设置、专业指导、低/中密度训练、> 24 次会议和持续 > 30 分钟的课程,对不同的认知领域更有效。本研究支持 DTI 在改善 60 岁及以上老年人认知功能方面的有效性,这可能受到研究设计和干预特征的影响。 这些发现对针对特定认知领域的临床痴呆预防和治疗策略具有重要意义。