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Lipid Trafficking in Diverse Bacteria
Accounts of Chemical Research ( IF 16.4 ) Pub Date : 2024-12-16 , DOI: 10.1021/acs.accounts.4c00540
Jonathan Chiu-Chun Chou, Laura M. K. Dassama

Lipids are essential for life and serve as cell envelope components, signaling molecules, and nutrients. For lipids to achieve their required functions, they need to be correctly localized. This requires the action of transporter proteins and an energy source. The current understanding of bacterial lipid transporters is limited to a few classes. Given the diversity of lipid species and the predicted existence of specific lipid transporters, many more transporters await discovery and characterization. These proteins could be prime targets for modulators that control bacterial cell proliferation and pathogenesis.

中文翻译:


不同细菌的脂质运输



脂质对生命至关重要,是细胞包膜成分、信号分子和营养物质。为了使脂质实现其所需的功能,需要正确定位它们。这需要转运蛋白和能量来源的作用。目前对细菌脂质转运蛋白的理解仅限于几类。鉴于脂质种类的多样性和特定脂质转运蛋白的预测存在,还有更多转运蛋白有待发现和表征。这些蛋白质可能是控制细菌细胞增殖和发病机制的调节剂的主要靶标。
更新日期:2024-12-16
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