Antibiotics are crucial in modern medicine for combating bacterial illnesses and saving lives. Still, their overuse has led to the rise of antibiotic-resistant bacteria, creating a serious public health risk. This study offers a unique approach for synthesizing a SnO2/MoO3 composite via precipitation and integrating it with commercial carbon black (CB) to make a SnO2/MoO3/CB composite. This substantially increases electrochemical detection, especially for antibiotics like furazolidone (FZD). The study uses multiple spectroscopic techniques to thoroughly characterize the SnO2/MoO3/CB composite, demonstrating its potential as an electrochemical sensor. We used a screen-printed carbon electrode (SPCE) to detect FZD. We found that the composite performed exceptionally well, with a detection limit of 0.01 µM owing to the enhanced surface area of the proposed sensor related to other modified electrodes. The sensor demonstrated good sensitivity (4.125 µA µM−1 cm−2) and selectivity and excellent real-time detection capability FZD in water samples, urine, and pharmaceutical samples. In these real-world samples, the SnO2/MoO3/CB@SPCE sensor also showed outstanding selectivity and recovery rates for FZD. This paper demonstrates a substantial advancement in the development of SnO2/MoO3/CB-SPCE sensors for antibiotic detection, with important implications for healthcare and environmental monitoring.

中文翻译：

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呋喃唑酮的高性能电化学检测：研究 SnO2/MoO3 与炭黑复合材料的协同效应


抗生素在现代医学中对于对抗细菌性疾病和挽救生命至关重要。尽管如此，它们的过度使用还是导致了抗生素耐药细菌的兴起，造成了严重的公共卫生风险。本研究提供了一种独特的方法，通过沉淀合成 SnO2/MoO3 复合材料，并将其与商业炭黑 （CB） 集成以制备 SnO2/MoO3/CB 复合材料。这大大提高了电化学检测，尤其是对于呋喃唑酮 （FZD） 等抗生素。该研究使用多种光谱技术对 SnO2/MoO3/CB 复合材料进行了全面表征，展示了其作为电化学传感器的潜力。我们使用丝网印刷碳电极 （SPCE） 检测 FZD。我们发现复合材料的性能非常好，由于所提出的传感器与其他改性电极相关的表面积增加，检测限为 0.01 μM。该传感器在水样、尿液和药物样品中表现出良好的灵敏度 （4.125 μA μM-1 cm-2） 和选择性以及出色的实时检测能力 FZD。在这些实际样品中，SnO2/MoO3/CB@SPCE 传感器对 FZD 也表现出出色的选择性和回收率。本文展示了用于抗生素检测的 SnO2/MoO3/CB-SPCE 传感器的开发取得了重大进展，对医疗保健和环境监测具有重要意义。