Eyelid pressure is a crucial biomechanical parameter for ocular health and refractive status, yet measuring it poses challenges related to flexibility, sensitivity, and regional specificity. This study introduces a novel smart contact lens that incorporates kirigami designs and an iontronic capacitive sensing array to enhance flexibility and conformability. The unique structural composition of this device allows for precise and simultaneous monitoring of eyelid pressure in multiple regions with a high sensitivity and seamlessly fit across corneal curvatures. The efficacy of the sensor has been thoroughly confirmed through comprehensive evaluations in rabbits and porcine eyes, demonstrating improved conformity and sensitivity compared to conventional single-point sensors. Assessments have been conducted in various conditions, including under anesthesia and in awake states, as well as the deliberate alteration of intraocular pressure fluctuations, all affirming the exceptional accuracy in detecting eyelid pressure. We envision that the smart contact lens has the potential to revolutionize diagnosis and management of eyelid-related ocular diseases.

中文翻译：

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Kirigami Design 智能隐形眼镜，用于高灵敏度眼睑压力测量


眼睑压力是影响眼部健康和屈光状态的关键生物力学参数，但测量它带来了与柔韧性、敏感性和区域特异性相关的挑战。本研究介绍了一种新型智能隐形眼镜，它结合了 kirigami 设计和离子电子电容传感阵列，以增强灵活性和顺应性。该设备独特的结构成分允许以高灵敏度精确和同时监测多个区域的眼睑压力，并无缝贴合角膜曲率。通过在兔子和猪眼中进行综合评估，该传感器的有效性已得到彻底证实，与传统的单点传感器相比，其一致性和灵敏度都有所提高。在各种条件下进行了评估，包括麻醉和清醒状态，以及故意改变眼压波动，所有这些都证实了检测眼睑压力的非凡准确性。我们设想智能隐形眼镜有可能彻底改变眼睑相关眼部疾病的诊断和管理。