BACKGROUND It remains unclear what proportion of patients with tricuspid regurgitation (TR) are suitable candidates for transcatheter tricuspid valve intervention (TTVI) in clinical practice. OBJECTIVES The aim of this study was to ascertain the prevalence of eligibility for tricuspid transcatheter edge-to-edge repair (T-TEER) and transcatheter tricuspid valve replacement (TTVR) devices among patients with TR. METHODS The tricuspid valve anatomy of all consecutive patients with TR who were considered for TTVI in local heart team conferences was retrospectively reviewed. According to current expert consensus, the anatomical feasibility for T-TEER was classified into 3 groups: favorable, feasible, and unfavorable anatomy. Clinical and anatomical eligibility for TTVR was evaluated in patients with cardiac computed tomographic (CCT) images. RESULTS Among 491 patients, 99 (20.2%) and 235 (47.9%) were considered to have favorable and feasible anatomy for T-TEER, respectively. In contrast, 157 patients (32.0%) had unfavorable anatomy for T-TEER. The most common reason for unfavorable anatomy for T-TEER was large coaptation gap width (66.2%), followed by anteroposterior TR jet location (62.4%). Among 327 patients with CCT images, 205 (62.7%) were judged to be clinically or anatomically ineligible for TTVR, mainly because of tricuspid annuli larger than commercially available prosthesis sizes (65.4%). Combined echocardiographic and CCT assessment showed that 23.2% of the patients with TR were ineligible for both T-TEER and TTVR. CONCLUSIONS Of 491 patients requiring TTVI, 32.0% had unfavorable anatomy for T-TEER, and 37.3% of patients with CCT images were eligible for TTVR. Despite the emergence of TTVR devices, 23.2% of patients with TR remained ineligible for both T-TEER and TTVR.

中文翻译：

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三尖瓣反流患者经导管三尖瓣干预的资格。


背景 目前尚不清楚在临床实践中，有多少比例的三尖瓣反流 （TR） 患者适合经导管三尖瓣介入治疗 （TTVI）。目的 本研究的目的是确定 TR 患者接受三尖瓣经导管边缘对边缘修复 （T-TEER） 和经导管三尖瓣置换术 （TTVR） 装置的资格的患病率。方法 回顾性回顾了在当地心脏团队会议上考虑进行 TTVI 的所有连续 TR 患者的三尖瓣解剖结构。根据目前的专家共识，T-TEER 的解剖学可行性分为 3 组：有利、可行和不利的解剖结构。在具有心脏计算机断层扫描 （CCT） 图像的患者中评估 TTVR 的临床和解剖学资格。结果 在 491 例患者中，分别有 99 例 （20.2%） 和 235 例 （47.9%） 被认为具有适合 T-TEER 和可行的解剖结构。相比之下，157 例患者 （32.0%） 的解剖结构对 T-TEER 不利。T-TEER 解剖结构不利的最常见原因是接合间隙宽度大 （66.2%），其次是前后 TR 射流位置 （62.4%）。在 327 名有 CCT 图像的患者中，205 名 （62.7%） 被判断为临床或解剖学上不符合 TTVR 条件，主要是因为三尖瓣环大于市售假体尺寸 （65.4%）。超声心动图和 CCT 联合评估显示，23.2% 的 TR 患者不符合 T-TEER 和 TTVR 的条件。结论 在 491 例需要 TTVI 的患者中，32.0% 的解剖结构不适合 TTER，37.3% 的有 CCT 图像的患者适合 TTVR。尽管出现了 TTVR 设备，但 23.2% 的 TR 患者仍然不符合 T-TEER 和 TTVR 的条件。