Extract

Pneumococcal pneumonia remains an important clinical problem. Globally, Streptococcus pneumoniae is the organism responsible for the largest proportion of lower respiratory tract infections and associated deaths [1]. Serotype replacement driven by vaccination programmes, non-response to vaccination in some individuals, and inequitable global availability of vaccines and treatment all contribute to persistently high rates of morbidity and mortality. Around 25% of patients require admission to an intensive care unit, 7% will require invasive mechanical ventilation, and 6% will die in hospital [2].

中文翻译：

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肺炎球菌肺炎中宿主葡萄糖的细菌挪用

 提取

肺炎球菌肺炎仍然是一个重要的临床问题。在全球范围内，肺炎链球菌是导致下呼吸道感染和相关死亡比例最大的微生物 [1]。疫苗接种计划驱动的血清型替代、一些人对疫苗接种无反应以及全球疫苗和治疗供应不公平，都导致了持续的高发病率和死亡率。大约 25% 的患者需要收入 ICU，7% 需要有创机械通气，6% 的患者将在医院死亡 [2]。