Extract

We have read with great interest the article from Halpin et al. [1] showing that a single moderate COPD exacerbation in the year prior to COPD diagnosis significantly increases the risk of future exacerbations over the next 12 months, while more frequent or severe exacerbations prior to diagnosis are associated with a higher risk.

中文翻译：

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COPD 恶化是否有点燃效应？

 提取

我们饶有兴趣地阅读了 Halpin等人 [1] 的文章，该文章显示，在 COPD 诊断前一年内单次中度 COPD 恶化会显著增加未来 12 个月恶化的风险，而诊断前更频繁或更严重的恶化与更高的风险相关。