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Correction to “Discovery of the Selective Protein Kinase C-θ Kinase Inhibitor, CC-90005”
Journal of Medicinal Chemistry ( IF 6.8 ) Pub Date : 2024-12-12 , DOI: 10.1021/acs.jmedchem.4c02898 Patrick Papa, Brandon Whitefield, Deborah S. Mortensen, Dan Cashion, Dehua Huang, Eduardo Torres, Jason Parnes, John Sapienza, Joshua Hansen, Matthew Correa, Mercedes Delgado, Roy Harris, Sayee Hegde, Stephen Norris, Sogole Bahmanyar, Veronique Plantevin-Krenitsky, Zheng Liu, Katerina Leftheris, Ashutosh Kulkarni, Brydon Bennett, Eun Mi Hur, Garth Ringheim, Godrej Khambatta, Henry Chan, Jeffrey Muir, Kate Blease, Kelven Burnett, Laurie LeBrun, Lisa Morrison, Maria Celeridad, Roli Khattri, Brian E. Cathers
Journal of Medicinal Chemistry ( IF 6.8 ) Pub Date : 2024-12-12 , DOI: 10.1021/acs.jmedchem.4c02898 Patrick Papa, Brandon Whitefield, Deborah S. Mortensen, Dan Cashion, Dehua Huang, Eduardo Torres, Jason Parnes, John Sapienza, Joshua Hansen, Matthew Correa, Mercedes Delgado, Roy Harris, Sayee Hegde, Stephen Norris, Sogole Bahmanyar, Veronique Plantevin-Krenitsky, Zheng Liu, Katerina Leftheris, Ashutosh Kulkarni, Brydon Bennett, Eun Mi Hur, Garth Ringheim, Godrej Khambatta, Henry Chan, Jeffrey Muir, Kate Blease, Kelven Burnett, Laurie LeBrun, Lisa Morrison, Maria Celeridad, Roli Khattri, Brian E. Cathers
In Figure 3 and the related text, Asp508 was incorrectly labeled as Asp409 due to typographical error in figure preparation. The corrected figure and updated line of text are as follow: Figure 3. Docking model of 3 bound in the ATP pocket of PKC-θ (PDB ID 1XJD used for docking studies). Page 11889: “The basic piperidine amine forms two salt-bridges with side-chain carboxylates of Asp465 and catalytic residue Asp522 and forms a third hydrogen bond to the backbone carbonyl of Asp508.” This article has not yet been cited by other publications.
中文翻译:
更正为“选择性蛋白激酶 C-θ 激酶抑制剂 CC-90005 的发现”
在图 3 和相关文本中,由于图准备中的印刷错误,Asp508 被错误地标记为 Asp409。更正后的数字和更新的文本行如下:图 3.3 结合在 PKC-θ 的 ATP 口袋中的对接模型(PDB ID 1XJD 用于对接研究)。第 11889 页:“碱性哌啶胺与 Asp465 的侧链羧酸盐和催化残基 Asp522 形成两个盐桥,并与 Asp508 的主链羰基形成第三个氢键。本文尚未被其他出版物引用。
更新日期:2024-12-12
中文翻译:
更正为“选择性蛋白激酶 C-θ 激酶抑制剂 CC-90005 的发现”
在图 3 和相关文本中,由于图准备中的印刷错误,Asp508 被错误地标记为 Asp409。更正后的数字和更新的文本行如下:图 3.3 结合在 PKC-θ 的 ATP 口袋中的对接模型(PDB ID 1XJD 用于对接研究)。第 11889 页:“碱性哌啶胺与 Asp465 的侧链羧酸盐和催化残基 Asp522 形成两个盐桥,并与 Asp508 的主链羰基形成第三个氢键。本文尚未被其他出版物引用。