The Fourth Universal Definition of Myocardial Infarction recommends a classification based on aetiology, in recognition that the underlying pathophysiology of myocardial infarction influences the approach to investigation and treatment. Type 1 myocardial infarction occurs due to atherosclerotic plaque rupture with thrombosis, whereas type 2 myocardial infarction occurs due to an imbalance in myocardial oxygen supply or unmet need in myocardial oxygen demand, without atherothrombosis, usually in the context of another acute illness. In this state-of-the-art review, the diagnosis, investigation, and treatment of patients with type 2 myocardial infarction are considered, with general advice for clinical practice and a consideration of future research directions.

中文翻译：

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2 型心肌梗死：诊断和治疗的挑战


《心肌梗死第四个通用定义》建议根据病因进行分类，因为认识到心肌梗死的潜在病理生理学会影响检查和治疗方法。1 型心肌梗死是由于动脉粥样硬化斑块破裂伴血栓形成而发生的，而 2 型心肌梗死是由于心肌氧供应失衡或心肌需氧需求未得到满足而发生，而没有动脉粥样硬化血栓形成，通常在另一种急性疾病的情况下发生。在这项最先进的综述中，考虑了 2 型心肌梗死患者的诊断、调查和治疗，并为临床实践提供了一般建议，并考虑了未来的研究方向。