Considering the increasing abundance of antibiotic-resistant bacteria, novel antimicrobial approaches need to be investigated. Photothermal therapy (PTT), an innovative noninvasive therapeutic technique, has demonstrated significant potential in addressing drug-resistant bacteria and bacterial biofilms. However, when used in isolation, PTT requires higher-temperature conditions to effectively eradicate bacteria, thereby potentially harming healthy tissues and inducing new inflammation. This study aims to present a comprehensive review of nanomaterials with intrinsic antimicrobial properties, antimicrobial materials relying on photothermal action, and nanomaterials using drug delivery antimicrobial action, along with their applications in antimicrobials. Additionally, the synergistic mechanisms of these antimicrobial approaches are elucidated. The review provides a reference for developing multifunctional photothermal nanoplatforms for treating bacterially infected wounds.

中文翻译：

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基于光热作用的抗菌材料及其在伤口治疗中的应用


考虑到抗生素耐药细菌的丰度不断增加，需要研究新的抗菌方法。光热疗法 （PTT） 是一种创新的无创治疗技术，在解决耐药细菌和细菌生物膜方面已显示出巨大潜力。然而，当单独使用时，PTT 需要更高的温度条件才能有效根除细菌，从而可能伤害健康组织并诱发新的炎症。本研究旨在全面回顾具有内在抗菌特性的纳米材料、依赖光热作用的抗菌材料、使用药物递送抗菌作用的纳米材料，以及它们在抗菌剂中的应用。此外，阐明了这些抗菌方法的协同机制。本文为开发用于治疗细菌感染伤口的多功能光热纳米平台提供了参考。