Background and objective

Our aim was to examine worldwide patterns and trends for prostate cancer (PC) incidence and mortality using high-quality, up-to-date, population-based data.

Methods

We analyzed age-standardized PC incidence and mortality rates by country and region from the 2022 GLOBOCAN estimates and temporal trends in incidence (50 countries/territories) and mortality (59 countries/territories) rates using data from the Cancer Incidence in Five Continents series and the World Health Organization mortality database.

Key findings and limitations

Estimated PC rates across regions in 2022 varied 13-fold for incidence and 9.5-fold for mortality. The highest incidence rates were in Australia/New Zealand, North America, Northern Europe, and Latin America/Caribbean. The highest mortality rates were in sub-Saharan Africa and Latin America/Caribbean. During the most recent 5-yr period, incidence rates increased in 11 of the 50 countries included in the study and mortality rates increased in nine of 59 countries, mostly located in Africa, Asia, Latin America/Caribbean, and Central and Eastern Europe. Mortality rates decreased in 38 countries, largely located in Europe, Oceania, and Latin America/Caribbean. Limitations include the lack of data for low- and middle-income countries.

Conclusions and clinical implications

The increase in PC incidence and mortality rates in many countries in Africa, Asia, and Latin America/Caribbean may be because of increases in detection (incidence) and limited access to and availability of treatments (mortality only). The findings reinforce the importance of improving the health care infrastructure in these countries to mitigate the rising burden of PC.

中文翻译：

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全球前列腺癌发病率和死亡率的最新模式和趋势：最新

 背景和目标

我们的目标是使用高质量、最新的、基于人群的数据来检查前列腺癌 （PC） 发病率和死亡率的全球模式和趋势。

 方法

我们使用来自五大洲癌症发病率系列和世界卫生组织死亡率数据库的数据，分析了 2022 年 GLOBOCAN 估计中按国家和地区划分的年龄标准化 PC 发病率和死亡率，以及发病率（50 个国家/地区）和死亡率（59 个国家/地区）的时间趋势。

主要发现和局限性

2022 年各地区估计的 PC 发病率变化了 13 倍，死亡率变化了 9.5 倍。发病率最高的是澳大利亚/新西兰、北美、北欧和拉丁美洲/加勒比地区。死亡率最高的是撒哈拉以南非洲和拉丁美洲/加勒比地区。在最近的 5 年期间，研究包括 50 个国家中有 11 个国家的发病率增加，59 个国家中有 9 个国家的死亡率增加，主要位于非洲、亚洲、拉丁美洲/加勒比地区以及中欧和东欧。38 个国家的死亡率下降，主要位于欧洲、大洋洲和拉丁美洲/加勒比地区。局限性包括缺乏低收入和中等收入国家的数据。

结论和临床意义

在非洲、亚洲和拉丁美洲/加勒比地区的许多国家，PC 发病率和死亡率的增加可能是由于检出率（发病率）的增加以及治疗的可及性和可及性有限（仅死亡率）。研究结果强调了改善这些国家医疗保健基础设施以减轻 PC 负担增加的重要性。