Asthma affects over 20 million (8%) of adults in the United States (US) each year.1 2 As with many chronic conditions, poor control can be attributed to low medication adherence and a reduced quality of life, and can translate into a high burden on the healthcare system and economy.3 4 Of importance is cost-related medication nonadherence, as people face heavy financial barriers to accessing US healthcare, on top of the chronic condition itself posing a major financial burden. Prescribed medications make up a considerable proportion of chronic disease spending in the US, particularly for asthma-related spending (~50% of asthma spending).4 Therefore, efforts to reduce cost-related medication nonadherence not only lessen the financial burden on the US health system but also support people’s ability to improve their disease symptoms. Recent research looking at cost-related medication nonadherence among people experiencing chronic disease has focused on coronary heart disease,5 liver disease,6 and chronic obstructive pulmonary disease (COPD)7 for example, but less so for asthma. Therefore in this issue of Thorax , Hung et al 8 fill the knowledge gap by conducting a study investigating the burden of cost-related medication nonadherence among a representative sample of 30 793 people with current asthma in the US. Using questionnaire data from the National Health Interview Survey (NHIS) from 2011 to 2022, the authors were specifically interested in examining the yearly trends in prevalence of cost-related medication nonadherence, the factors associated with cost-related medication nonadherence, and the association …

中文翻译：

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美国哮喘患者与成本相关的不依从药物治疗：加强历史和医疗保健改革相关性的发现


哮喘每年影响美国 （US） 超过 2000 万 （8%） 的成年人。1 2 与许多慢性病一样，控制不佳可归因于低服药依从性和生活质量下降，并可能转化为医疗保健系统和经济的沉重负担。3 4 重要的是与成本相关的药物不依从性， 由于人们在获得美国医疗保健方面面临沉重的经济障碍，此外，慢性病本身也构成了重大的经济负担。处方药在美国慢性病支出中占相当大的比例，尤其是与哮喘相关的支出（占哮喘支出的 ~50%）.4 因此，减少与成本相关的药物不依从性的努力不仅减轻了美国卫生系统的经济负担，还支持人们改善疾病症状的能力。最近关于慢性病患者与成本相关的药物不依从性的研究主要集中在冠心病5、肝病6 和慢性阻塞性肺病 （COPD）7 等问题上，但对哮喘的关注较少。因此，在本期 Thorax 中，Hung 等人 8 通过进行一项研究来填补知识空白，该研究调查了美国 30 793 名当前哮喘患者的代表性样本中与成本相关的药物不依从性负担。使用 2011 年至 2022 年全国健康访谈调查 （NHIS） 的问卷数据，作者对检查与成本相关的药物不依从性患病率的年度趋势、与成本相关的药物不依从性相关的因素以及关联特别感兴趣......