PD-1 pathway blockade in combination with chemotherapy has emerged as a treatment paradigm for patients with resectable lung cancer, but insights into predictive biomarkers and mechanisms of immune responses are lacking. A study uses spatial transcriptomic methods to identify patterns within the tumor microenvironment associated with response.

中文翻译：

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空间生物学捕捉新辅助化疗免疫疗法对肺癌的影响


PD-1 通路阻断联合化疗已成为可切除肺癌患者的治疗范例，但缺乏对预测性生物标志物和免疫反应机制的见解。一项研究使用空间转录组学方法来识别肿瘤微环境中与反应相关的模式。