The CRISPR/Cas genome editing technology, with its advantages of simplicity, high efficiency, and cost‐effectiveness, has become a key tool for dissecting gene function, knocking out harmful/undesirable genes, and repairing defective genes. It has also shown great potential in the genome editing of aquatic animals such as tilapia, carp, salmon, and sea urchins. Disease prevention and control are core areas of aquatic animal research and the aquaculture industry. Novel technologies based on CRISPR/Cas, such as rapid diagnostic kits for aquatic diseases and species‐specific drugs against parasites, have been developed in the disease diagnosis, treatment, and prevention of aquatic animals. Based on our work in these fields, this review summarizes the relevant new technologies and latest progress, aiming to provide readers with a quick and comprehensive understanding of the application status and future trends of CRISPR/Cas technology in the prevention and control of aquatic diseases and to provide a reference for related fields.

中文翻译：

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CRISPR/Cas技术在水生动物疾病防控中的应用


CRISPR/Cas 基因组编辑技术具有简单、高效、成本效益高等优点，已成为解剖基因功能、敲除有害/不良基因和修复缺陷基因的关键工具。它在罗非鱼、鲤鱼、鲑鱼和海胆等水生动物的基因组编辑中也显示出巨大的潜力。疾病预防和控制是水生动物研究和水产养殖业的核心领域。基于 CRISPR/Cas 的新技术，如水生疾病快速诊断试剂盒和针对寄生虫的物种特异性药物，已经在水生动物的疾病诊断、治疗和预防中被开发出来。本文结合我们在这些领域的工作，总结了相关的新技术和最新进展，旨在为读者提供对CRISPR/Cas技术在水生疾病防控中的应用现状和未来趋势的快速、全面的了解，为相关领域提供参考。