Collagen fiber purification is the most important pretreatment process in the recycling of animal hide/skin, by-products of meat production, and can be utilized to produce value-added materials. Traditional animal hide/skin resource utilization technologies face serious challenges in the aspect of production efficiency and environmental sustainability. Enzymatic collagen fiber purification processing is thought to be one of the most promising technologies that can minimize the use of chemicals and energy, reduce CO2-eq emissions, and achieve sustainable development of animal hide/skin reutilization. However, enzymatic processes have not been well accepted for industrial-scale applications in factories so far. In this review, recent progress and challenges of enzymatic collagen fiber purification processing were comprehensively overviewed in the aspect of the key mechanisms and technologies of enzyme application. Recommendations for the direction of enzyme selection and development were put forward, which is expected to pave the way for the industrial-scale application of enzymes in animal hide/skin collagen fiber purification processing.

中文翻译：

---

动物皮/皮胶原纤维纯化加工的酶法工艺：最新进展、挑战和建议


胶原纤维纯化是动物毛皮（肉类生产副产品）回收中最重要的前处理工艺，可用于生产增值材料。传统的动物毛皮资源利用技术在生产效率和环境可持续性方面面临严峻挑战。酶促胶原纤维纯化加工被认为是最有前途的技术之一，可以最大限度地减少化学品和能源的使用，减少 CO2-eq 排放，并实现动物毛皮再利用的可持续发展。然而，到目前为止，酶法工艺尚未被广泛接受于工厂的工业规模应用。本文从酶应用的关键机制和技术方面全面综述了酶法胶原纤维纯化加工的最新进展和面临的挑战。对酶的选择和发展方向提出了建议，有望为酶在动物皮/皮胶原纤维纯化加工中的工业化应用铺平道路。