Localized surface plasmon resonance (LSPR) sensor has drawn continuous attention to application of the detection of antibody, protein, virus, and bacteria. However, natural recognition molecules, such as antibody, which possess some properties, including low thermal stability, complicated operation and high price, uncontrollability of length and size and a tendency to accumulate easily on the surface of chip to reduce the sensitive of method. Furthermore, common blocking agents are not suitable for development of novel biosensors. There is a significant demand for an innovative artificial probe that can meet the high recognition capabilities and ultrasensitive required by LSPR sensors.

中文翻译：

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在局部表面等离子体共振平台上使用 Y 形 DNA 归巢肽掺杂探针对纤维蛋白进行超灵敏、高选择性的检测


局域表面等离子体共振 （LSPR） 传感器在抗体、蛋白质、病毒和细菌检测中的应用引起了人们的持续关注。然而，抗体等自然识别分子具有热稳定性低、操作复杂、价格高、长度和大小不可控、易积聚在芯片表面以降低方法敏感性等特性。此外，常见的封闭剂不适合开发新型生物传感器。对能够满足 LSPR 传感器所需的高识别能力和超灵敏的创新人工探头的需求很大。