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Removing "flavor" from pathogenic antibodies hits a therapeutic sweet spot.
Science Immunology ( IF 17.6 ) Pub Date : 2024-12-06 , DOI: 10.1126/sciimmunol.adu8805
Dana L E Vergoossen,Maartje G Huijbers

Endoglycosidase CU43 removes IgG Fc glycans, inhibits IgG effector functions, and prevents pathology in multiple disease models.

中文翻译:


从致病性抗体中去除“味道”触及了治疗的最佳点。



内切糖苷酶 CU43 可去除 IgG Fc 聚糖,抑制 IgG 效应子功能,并在多种疾病模型中预防病理。
更新日期:2024-12-06
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