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Association of ten VEGF family genes with Alzheimer's disease endophenotypes at single cell resolution
Alzheimer's & Dementia ( IF 13.0 ) Pub Date : 2024-12-06 , DOI: 10.1002/alz.14419
Yiyang Wu, Julia B. Libby, Logan Dumitrescu, Philip L. De Jager, Vilas Menon, Julie A. Schneider, David A. Bennett, Timothy J. Hohman

Using a single-nucleus transcriptome derived from the dorsolateral prefrontal cortex of 424 Religious Orders Study and the Rush Memory and Aging Project (ROS/MAP) participants, we investigated the cell type–specific effect of ten vascular endothelial growth factor (VEGF) genes on Alzheimer's disease (AD) endophenotypes.

中文翻译:


10 个 VEGF 家族基因与单细胞分辨率下阿尔茨海默病内表型的相关性



使用源自 424 个宗教秩序研究和 Rush Memory and Aging Project (ROS/MAP) 参与者背外侧前额叶皮层的单核转录组,我们研究了 10 个血管内皮生长因子 (VEGF) 基因对阿尔茨海默病 (AD) 内表型的细胞类型特异性影响。
更新日期:2024-12-06
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