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Lactylation as a post-translational regulator of cGAS and immunity
Molecular Cell ( IF 14.5 ) Pub Date : 2024-12-05 , DOI: 10.1016/j.molcel.2024.11.018
Haipeng Liu, Baoxue Ge

In a recent paper at Nature, Li et al.1 reported that alanine-tRNA synthetases AARS1 and AARS2 are lactate sensors and mediate lactylation of cGAS, leading to its inactivation.

中文翻译:


乳酰化作为 cGAS 和免疫的翻译后调节因子



在最近发表在《自然》杂志上的一篇论文中,Li 等人1 报道了丙氨酸-tRNA 合成酶 AARS1 和 AARS2 是乳酸传感器,介导 cGAS 的乳酰化,导致其失活。
更新日期:2024-12-05
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