Extract

We have cured chronic lung diseases, including COPD, in mice many times. However, translation to clinical application has failed in most cases. Why is this the case and what can we do about it? One of the reasons for this is that mice are simply not small humans. Developing novel human lung models will help us in identifying more promising novel therapeutic strategies, thereby hopefully leading to therapeutic options that translate to the clinic.

中文翻译：

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未来的呼吸：一种用于 COPD 及其他疾病的新型人体模型

 提取

我们已经多次治愈了小鼠的慢性肺部疾病，包括 COPD。然而，在大多数情况下，转化为临床应用是失败的。为什么会这样，我们能做些什么？原因之一是老鼠根本不是小人。开发新的人类肺部模型将帮助我们确定更有前途的新型治疗策略，从而有望带来转化为临床的治疗选择。