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Regional cerebral blood flow reflects both neurodegeneration and microvascular integrity across the Alzheimer's continuum
Alzheimer's & Dementia ( IF 13.0 ) Pub Date : 2024-12-03 , DOI: 10.1002/alz.14382 Mohammad Taghvaei, Sudipto Dolui, Shokufeh Sadaghiani, Banafsheh Shakibajahromi, Christopher Brown, Pulkit Khandelwal, Sharon X. Xie, Sandhitsu Das, Paul A. Yushkevich, David A. Wolk, John A. Detre
Alzheimer's & Dementia ( IF 13.0 ) Pub Date : 2024-12-03 , DOI: 10.1002/alz.14382 Mohammad Taghvaei, Sudipto Dolui, Shokufeh Sadaghiani, Banafsheh Shakibajahromi, Christopher Brown, Pulkit Khandelwal, Sharon X. Xie, Sandhitsu Das, Paul A. Yushkevich, David A. Wolk, John A. Detre
Alzheimer's disease (AD) typically involves both neurodegenerative and vascular pathologies, each associated with reductions in cerebral blood flow (CBF). However, it remains unclear whether vascular and neural contributions to regional CBF can be differentiated.
中文翻译:
区域脑血流反映了阿尔茨海默病连续体中的神经退行性和微血管完整性
阿尔茨海默病 (AD) 通常涉及神经退行性和血管病变,每一种都与脑血流量 (CBF) 的减少有关。然而,目前尚不清楚血管和神经对区域 CBF 的贡献是否可以区分。
更新日期:2024-12-03
中文翻译:

区域脑血流反映了阿尔茨海默病连续体中的神经退行性和微血管完整性
阿尔茨海默病 (AD) 通常涉及神经退行性和血管病变,每一种都与脑血流量 (CBF) 的减少有关。然而,目前尚不清楚血管和神经对区域 CBF 的贡献是否可以区分。