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A cautionary tale for Alzheimer’s disease GWAS by proxy
Nature Genetics ( IF 31.7 ) Pub Date : 2024-12-02 , DOI: 10.1038/s41588-024-02023-y
Emil M. Pedersen, Theresa Wimberley, Bjarni J. Vilhjálmsson

Using reported parental disease history to decipher the genetics of Alzheimer’s disease may be promising, but this approach is also susceptible to complex selection and information bias that can mislead researchers if not accounted for.

中文翻译:


代理阿尔茨海默病 GWAS 的警示故事



使用报告的父母疾病史来破译阿尔茨海默病的遗传学可能是有希望的,但这种方法也容易受到复杂选择和信息偏差的影响,如果不加以考虑,可能会误导研究人员。
更新日期:2024-12-02
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