The exhaled H₂S gas is considered a promising noninvasive, rapid biomarker for diagnosing oral health and respiratory diseases. However, there is an urgent need in the healthcare industry for a sensitive, accurate, low-cost, and comfortable wearable breath sensor for H₂S detection. Herein, a Janus wettable mask was developed by integrating the ratiometric fluorescent probes and asymmetric wettable fabric into the interior of the mask, for the comfortable and visual detection of H₂S. The Janus wettable mask with unidirectional biofluid transport capabilities can quickly transfer liquids from the hydrophobic side to the hydrophilic side, ensuring the dryness of the face during prolonged mask wear. The fluorescent color change from red to blue on the mask sensor can be observed by the naked eye under ultraviolet light, which enables evaluation of the H₂S gas concentration within a linear range of 1–100 ppb, and a low detection limit of 0.8 ppb. On-body experiments confirmed that the mask accurately detects exhaled H₂S gas and effectively captures the dynamic variations in H₂S gas levels at different times of the day. This study provides new insights into developing user-friendly wearable sensors and offers innovative solutions for reducing the burden on healthcare systems.

中文翻译：

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Janus 可湿性面罩，集成比例荧光探针，用于舒适地呼出 H2S 气体传感


呼出的 H₂S 气体被认为是一种很有前途的无创、快速生物标志物，用于诊断口腔健康和呼吸系统疾病。然而，医疗保健行业迫切需要一种灵敏、准确、低成本和舒适的可穿戴式呼吸传感器，用于 H₂S 检测。在此，通过将比率荧光探针和不对称可湿性织物集成到口罩内部，开发了一种 Janus 可湿性口罩，用于舒适、直观地检测 H₂S。Janus 可湿性口罩具有单向生物流体运输能力，可以将液体从疏水侧快速转移到亲水侧，确保在长时间佩戴口罩时面部干燥。在紫外光下，肉眼可以观察到掩模传感器上从红色到蓝色的荧光颜色变化，从而能够在 1-100 ppb 的线性范围内评估 H₂S 气体浓度，检测限为 0.8 ppb。身上实验证实，该口罩准确检测呼出的 H₂S 气体，并有效捕捉一天中不同时间 H₂S 气体水平的动态变化。本研究为开发用户友好的可穿戴传感器提供了新的见解，并为减轻医疗保健系统的负担提供了创新解决方案。