Colorectal cancer remains a challenging heterogeneous disease with substantial morbidity and mortality. However, progressive advances over the past year have led to marked improvements and overcome challenges previously considered insurmountable. Here, we review key clinical trials in colorectal cancer in 2024, leading to personalized approaches in locally advanced and metastatic disease.

中文翻译：

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在局部晚期和转移性结直肠癌中转向更加个性化的方法


结直肠癌仍然是一种具有挑战性的异质性疾病，发病率和死亡率很高。然而，过去一年的进步带来了显着的进步，并克服了以前被认为无法克服的挑战。在这里，我们回顾了 2024 年结直肠癌的关键临床试验，从而在局部晚期和转移性疾病中采用个性化方法。