Electrolyte-gated field-effect transistors (EGFETs) based on transition metal dichalcogenides (TMDCs) are promising for biosensing applications due to their high transconductance (1.98 mS) and surface sensitivity enabling the detection of minute interfacial changes. However, their stability in aqueous poses significant challenges for long-term reliability. This work presents a study to anhance both the stability and performance of TMDC-based EGFETs. Initial devices showed promising performance but suffered significant instability during prolonged aqueos operation, limiting their biosensing applications. Postmortem analysis identified key areas for improvement leadinf to three major modifications: 1) a double-junction Ag/AgCl electrode to prevent ion leakage, 2) a protective resist layer to shields the monolayer, and 3) precise etching to confine the semiconductor material, reducing parasitic currents. These optimizations imroved the devices' transconductance and ensured stable operation over extended periods establishing TMDC-based EGFETs as viable candidates for reliable biosensing in aqueous environments.

中文翻译：

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优化 MoS2 电解质门控晶体管：稳定性、性能和灵敏度增强


基于过渡金属硫化物 （TMDC） 的电解质门控场效应晶体管 （EGFET） 因其高跨导 （1.98 mS） 和表面灵敏度而能够检测微小的界面变化，因此在生物传感应用中很有前途。然而，它们在水性中的稳定性对长期可靠性构成了重大挑战。这项工作提出了一项研究，以提高基于 TMDC 的 EGFET 的稳定性和性能。最初的设备显示出有希望的性能，但在长时间的 aqueos 操作过程中出现了明显的不稳定性，限制了它们的生物传感应用。尸检分析确定了需要改进的关键领域，导致了三个主要修改：1） 双结 Ag/AgCl 电极以防止离子泄漏，2） 保护性光刻胶层以屏蔽单层，以及 3） 精确蚀刻以限制半导体材料，减少寄生电流。这些优化提高了器件的跨导性，并确保了长时间的稳定运行，使基于 TMDC 的 EGFET 成为在水性环境中可靠生物传感的可行候选者。