PURPOSE The purpose of this project was to evaluate trends in daily steps in individuals with Parkinson's disease (PD) over a 12-month period using continuous activity monitoring. Environmental (temperature) and cultural factors (represented by day of the week) were evaluated as potential external sources of variability. It was hypothesized that participants daily step counts would decline over the course of 12 months. Further, it was hypothesized that participants would take more steps on warmer days and that the day of the week would have minimal impact on step count as many participants were no longer in the workforce. METHODS Participants were part of the Usual and Customary Care arm (N = 119) of the CYClical Lower Extremity Exercise Trial for Parkinson's disease - II (CYCLE-II) at the Cleveland Clinic and University of Utah. Participants wore a Garmin Vivofit4® device daily for 12-months. A linear mixed effects model was created to model daily steps over 12-months. RESULTS Participants wore their activity monitors 93% of study days. Steps per day declined by 6.1% over 12 months (95% CI 12.6% decline, 0.9% increase, p = 0.09). Steps per day were greater with warmer temperatures (p < 0.001), plateauing and declining around 75-85 degrees Fahrenheit (24-29 degrees Celsius). Participants took fewer steps on Sundays; this difference was more pronounced for Utah participants, who took 25% fewer steps on Sundays compared to other weekdays (p < 0.001). CONCLUSIONS Most individuals live with PD for decades, and interventions should address the expected decline of 6% in daily step count. Environmental and cultural factors impact daily step count and should be adjusted for in short- and long-term monitoring of physical activity in individuals with PD.

中文翻译：

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帕金森病 12 个月内身体活动下降：纵向活动监测的注意事项。


目的 该项目的目的是使用连续活动监测来评估帕金森病 （PD） 患者在 12 个月内的日常步数趋势。环境 （温度） 和文化因素 （以星期几表示） 被评估为潜在的外部变异源。据推测，参与者的每日步数将在 12 个月内下降。此外，假设参与者在温暖的日子里会走更多的步数，并且由于许多参与者不再工作，因此一周中的某一天对步数的影响最小。方法 参与者是克利夫兰诊所和犹他大学帕金森病 CYClical 下肢运动试验 - II （CYCLE-II） 的常规和惯常护理组 （N = 119） 的一部分。参与者每天佩戴 Garmin Vivofit4® 设备，持续 12 个月。创建了一个线性混合效应模型来模拟 12 个月内的每日步数。结果 参与者在 93% 的学习日都佩戴了他们的活动监测器。在 12 个月内，每天的步数下降了 6.1% （95% CI 下降 12.6%，增加 0.9%，p = 0.09）。随着温度升高（p < 0.001），每天的步数更大，在 75-85 华氏度（24-29 摄氏度）左右趋于稳定和下降。参与者在周日走的步数较少;这种差异对于犹他州的参与者来说更为明显，与其他工作日相比，他们在周日的步数减少了 25%（p < 0.001）。结论 大多数人患有 PD 数十年，干预措施应解决每日步数预期下降 6% 的问题。环境和文化因素会影响每日步数，应在短期和长期监测 PD 患者的身体活动时进行调整。