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Elevated locus coeruleus metabolism provides resilience against cognitive decline in preclinical Alzheimer's disease
Alzheimer's & Dementia ( IF 13.0 ) Pub Date : 2024-11-26 , DOI: 10.1002/alz.14385 Elouise A. Koops, Joyita Dutta, Bernard J. Hanseeuw, J. Alex Becker, Maxime Van Egroo, Prokopis C. Prokopiou, Julie C. Price, Steven E. Arnold, Reisa A. Sperling, Keith A. Johnson, Heidi I. L. Jacobs
Alzheimer's & Dementia ( IF 13.0 ) Pub Date : 2024-11-26 , DOI: 10.1002/alz.14385 Elouise A. Koops, Joyita Dutta, Bernard J. Hanseeuw, J. Alex Becker, Maxime Van Egroo, Prokopis C. Prokopiou, Julie C. Price, Steven E. Arnold, Reisa A. Sperling, Keith A. Johnson, Heidi I. L. Jacobs
Alterations in locus coeruleus’ (LC) metabolic turnover are associated with Alzheimer's disease (AD)-pathology and cognitive impairment. However, the evolution of these changes across disease stages and their functional relevance remains unknown.
中文翻译:
青斑代谢升高为临床前阿尔茨海默病的认知能力下降提供了弹性
蓝斑 (LC) 代谢周转的改变与阿尔茨海默病 (AD) 病理和认知障碍有关。然而,这些变化在不同疾病阶段的演变及其功能相关性仍然未知。
更新日期:2024-11-26
中文翻译:
青斑代谢升高为临床前阿尔茨海默病的认知能力下降提供了弹性
蓝斑 (LC) 代谢周转的改变与阿尔茨海默病 (AD) 病理和认知障碍有关。然而,这些变化在不同疾病阶段的演变及其功能相关性仍然未知。