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Design and synthesis of camphor-thiazole derivatives as potent antifungal agents: structure–activity relationship and preliminary mechanistic study
Pest Management Science ( IF 3.8 ) Pub Date : 2024-11-26 , DOI: 10.1002/ps.8563 Peng Dai, Zihua Ma, Yuncong Dang, Jiaxuan Huang, Huizhen Xue, Yafang Sun, Yu-Cheng Gu, Qing Xia, Weihua Zhang
Pest Management Science ( IF 3.8 ) Pub Date : 2024-11-26 , DOI: 10.1002/ps.8563 Peng Dai, Zihua Ma, Yuncong Dang, Jiaxuan Huang, Huizhen Xue, Yafang Sun, Yu-Cheng Gu, Qing Xia, Weihua Zhang
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Plant pathogenic fungi pose a severe threat to crop yield and food security. This study aims to investigate the potential antifungal activity and mechanism of action of camphor-thiazole derivatives against six plant pathogenic fungi. A novel series of camphor-thiazole derivatives were designed, synthesized and evaluated for their antifungal effects against Rhizoctonia solani, Fusarium graminearum, Valsa mali, Alternaria solani, Colletotrichum orbiculare and Botryitis cinerea.
中文翻译:
樟脑-噻唑衍生物作为有效抗真菌剂的设计与合成:构效关系和初步机理研究
植物病原真菌对作物产量和粮食安全构成严重威胁。本研究旨在探讨樟脑-噻唑衍生物对 6 种植物病原真菌的潜在抗真菌活性和作用机制。设计、合成了一系列新型樟脑-噻唑衍生物,并评价了它们对立枯丝核菌、禾谷镰刀菌、马里笙草、链格孢属、炭疽菌和灰葡萄孢菌的抑菌作用。
更新日期:2024-11-26
中文翻译:

樟脑-噻唑衍生物作为有效抗真菌剂的设计与合成:构效关系和初步机理研究
植物病原真菌对作物产量和粮食安全构成严重威胁。本研究旨在探讨樟脑-噻唑衍生物对 6 种植物病原真菌的潜在抗真菌活性和作用机制。设计、合成了一系列新型樟脑-噻唑衍生物,并评价了它们对立枯丝核菌、禾谷镰刀菌、马里笙草、链格孢属、炭疽菌和灰葡萄孢菌的抑菌作用。