A rising corpus of research has shown the beneficial effects of probiotic Lactobacilli on human health, contributing to the growing popularity of these microorganisms in recent decades. The gastrointestinal and urinary tracts are home to these bacteria, which play a vital role in the microbial flora of both humans and animals. The Lactobacillus probiotic, i.e, Lactobacillus plantarum, Lactobacillus paracasei, Lactobacillus acidophilus, Lactobacillus casei, Lactobacillus rhamnosus, Lactobacillus crispatus, Lactobacillus gasseri, Lactobacillus reuteri, and Lactobacillus bulgaricus, are highly recognized for their remarkable probiotic qualities. The current study aims to highlight the beneficial effects of probiotics in different health conditions, point out the research gap, and highlight the future directives for the safe use of these probiotics in several health issues. Most importantly, we have added the most recent literature related to the characteristics and usage of these probiotics in clinical and pre-clinical settings. Based on the above statement, we believe that this is the first report on the application of probiotics in human diseases. By providing a deeper knowledge of the complex functions these probiotics play in both human and animal health, our analysis will direct future studies and developments in this rapidly developing field.

中文翻译：

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乳酸菌菌株的益生菌意义：对健康影响、研究差距和未来前景的全面回顾。


越来越多的研究表明，益生菌乳酸杆菌对人类健康的有益作用，导致这些微生物在近几十年来越来越受欢迎。胃肠道和泌尿道是这些细菌的家园，这些细菌在人类和动物的微生物菌群中起着至关重要的作用。乳酸菌益生菌，即植物乳杆菌、副干酪乳杆菌、嗜酸乳杆菌、干酪乳杆菌、鼠李糖乳杆菌、脆皮乳杆菌、加氏乳杆菌、罗伊氏乳杆菌和保加利亚乳杆菌，因其卓越的益生菌品质而受到高度认可。目前的研究旨在强调益生菌在不同健康状况中的有益作用，指出研究空白，并强调在几个健康问题中安全使用这些益生菌的未来指令。最重要的是，我们添加了与这些益生菌在临床和临床前环境中的特性和用途相关的最新文献。基于以上陈述，我们认为这是益生菌在人类疾病中应用的首篇报告。通过更深入地了解这些益生菌在人类和动物健康中发挥的复杂功能，我们的分析将指导这一快速发展领域的未来研究和发展。