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2-Fold More Cardiovascular Disease Events Decades Before Type 2 Diabetes Diagnosis: A Nationwide Registry Study

2251Christine Gyldenkerne, Johnny Kahlert, Pernille G. Thrane, Kevin K.W. Olesen, Martin B. Mortensen, Henrik T. Sørensen, Reimar W. Thomsen, Michael MaengIn this large, nationwide, registry-based study, individuals with type 2 diabetes had 2-fold more cardiovascular disease events than age- and sex-matched comparisons from the general population. This increased cardiovascular disease occurrence started 3 decades before, and continued after, the clinical diagnosis of type 2 diabetes. Findings

Sudden Death in Obesity: Mechanisms and Management

2308Lauri Holmstrom, Juhani Junttila, Sumeet S. ChughObesity is a significant risk factor for cardiovascular diseases and most obesity-related premature deaths are due to cardiovascular causes. Approximately one-half of all deaths due to cardiac causes are sudden cardiac deaths (SCDs). Obesity and especially visceral fat increase the risk of SCD, and obesity-associated SCD is often accompanied by cardiac hypertrophy and CAD. However, the proximate causes and risk markers of SCD in obesity are

The Lancet–JACC Collaboration: Advancing Cardiovascular Health

2325Harlan M. Krumholz, Flávia Geraldes, Chloe Wilson, Richard Horton

Ambient Temperature and Stroke Risk Among Adults Aged 18-64 Years: A Case-Crossover Study

2327Lingzhi Chu, Rong Wang, Cary P. Gross, Kai Chen, Xiaomei Ma

Scattered Denial: Reflections on the Occupational Hazards and Health Risks Over a 35-Year Career in Interventional Cardiology

2332David G. Rizik

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2 型糖尿病诊断前几十年心血管疾病事件增加 2 倍：一项全国性的登记研究

2251 元Christine Gyldenkerne、Johnny Kahlert、Pernille G. Thrane、Kevin KW Olesen、Martin B. Mortensen、Henrik T. Sørensen、Reimar W. Thomsen、Michael Maeng在这项大型全国性、基于登记的研究中，2 型糖尿病患者的心血管疾病事件比普通人群的年龄和性别匹配的比较多 2 倍。这种心血管疾病发病率的增加始于 2 型糖尿病临床诊断之前的 3 年，并在 2 型糖尿病临床诊断之后持续存在。发现

肥胖猝死：机制和管理

2308 元Lauri Holmstrom， Juhani Junttila， Sumeet S. Chugh肥胖是心血管疾病的重要危险因素，大多数与肥胖相关的过早死亡是由于心血管原因造成的。大约一半的心脏原因导致的死亡是心源性猝死 （SCD）。肥胖，尤其是内脏脂肪会增加患 SCD 的风险，而肥胖相关的 SCD 通常伴有心脏肥大和 CAD。然而，肥胖症 SCD 的直接原因和风险标志物是

柳叶刀-JACC 合作：促进心血管健康

2325 元Harlan M. Krumholz、Flávia Geraldes、Chloe Wilson、Richard Horton

18-64 岁成年人的环境温度和中风风险：一项病例交叉研究

2327 元朱玲芝， 王荣， Cary P. Gross， 陈凯， 马小梅

分散否认：介入心脏病学 35 年职业生涯中对职业危害和健康风险的反思

2332 元大卫·里齐克