Transcatheter tricuspid valve replacement (TTVR) has emerged as a promising intervention for the treatment of severe tricuspid regurgitation with complex valve morphology. This consensus document provides a comprehensive overview of the current state of orthotopic TTVR, focusing on patient selection, procedural details, and follow-up care. Clinical outcomes from initial studies and compassionate use cases are discussed, highlighting the effectiveness of TTVR in reducing tricuspid regurgitation, inducing reverse right ventricular remodeling, and enhancing patients’ quality of life. This review paper also addresses potential complications and challenges associated with TTVR, such as new-onset conduction disturbances, bleeding complications, and afterload mismatch, and provides expert recommendations for the periprocedural management, anticoagulation strategies, and long-term follow-up. With the commercial approval of the first TTVR system in the United States and Europe, it intends to serve as a reference for clinicians and researchers involved in the evolving field of transcatheter tricuspid valve interventions.

中文翻译：

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经导管三尖瓣置换术


经导管三尖瓣置换术 （TTVR） 已成为治疗具有复杂瓣膜形态的严重三尖瓣反流的一种有前途的干预措施。本共识文件全面概述了原位 TTVR 的现状，重点关注患者选择、手术细节和随访护理。讨论了初步研究和富有同情心的使用案例的临床结果，强调了 TTVR 在减少三尖瓣反流、诱导反向右心室重塑和提高患者生活质量方面的有效性。本综述论文还讨论了与 TTVR 相关的潜在并发症和挑战，例如新发传导障碍、出血并发症和后负荷不匹配，并为围手术期管理、抗凝策略和长期随访提供了专家建议。随着第一个 TTVR 系统在美国和欧洲获得商业批准，它旨在为参与不断发展的经导管三尖瓣介入治疗的临床医生和研究人员提供参考。