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Benchmarking of a multi-biomarker low-volume panel for Alzheimer's disease and related dementia research
Alzheimer's & Dementia ( IF 13.0 ) Pub Date : 2024-11-22 , DOI: 10.1002/alz.14413 Laura Ibanez, Menghan Liu, Aleksandra Beric, Jigyasha Timsina, Pat Kohlfeld, Kristy Bergmann, Joey Lowery, Nick Sykora, Brenda Sanchez-Montejo, Will Brock, John P. Budde, Randall J. Bateman, Nicolas Barthelemy, Suzanne E. Schindler, David M. Holtzman, Tammie L. S. Benzinger, Chengjie Xiong, Rawan Tarawneh, Krista Moulder, John C. Morris, Yun Ju Sung, Carlos Cruchaga
Alzheimer's & Dementia ( IF 13.0 ) Pub Date : 2024-11-22 , DOI: 10.1002/alz.14413 Laura Ibanez, Menghan Liu, Aleksandra Beric, Jigyasha Timsina, Pat Kohlfeld, Kristy Bergmann, Joey Lowery, Nick Sykora, Brenda Sanchez-Montejo, Will Brock, John P. Budde, Randall J. Bateman, Nicolas Barthelemy, Suzanne E. Schindler, David M. Holtzman, Tammie L. S. Benzinger, Chengjie Xiong, Rawan Tarawneh, Krista Moulder, John C. Morris, Yun Ju Sung, Carlos Cruchaga
In the research setting, obtaining accurate established biomarker measurements and maximizing use of the precious samples is key. Accurate technologies are available for Alzheimer's disease (AD), but no platform can measure all the established and emerging biomarkers in one run. The NUcleic acid Linked Immuno-Sandwich Assay (NULISA) is a technology that requires 15 µL of sample to measure more than 100 analytes.
中文翻译:
阿尔茨海默病和相关痴呆研究的多生物标志物低容量面板的基准
在研究环境中,获得准确、既定的生物标志物测量值并最大限度地利用珍贵样本是关键。阿尔茨海默病 (AD) 有准确的技术,但没有一个平台可以一次性测量所有已建立和新出现的生物标志物。核酸联免疫夹心检测 (NULISA) 是一种需要 15 μL 样品来测量 100 多种分析物的技术。
更新日期:2024-11-22
中文翻译:

阿尔茨海默病和相关痴呆研究的多生物标志物低容量面板的基准
在研究环境中,获得准确、既定的生物标志物测量值并最大限度地利用珍贵样本是关键。阿尔茨海默病 (AD) 有准确的技术,但没有一个平台可以一次性测量所有已建立和新出现的生物标志物。核酸联免疫夹心检测 (NULISA) 是一种需要 15 μL 样品来测量 100 多种分析物的技术。