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ACBP orchestrates the metabolic phenotype in Cushing’s syndrome
Nature Metabolism ( IF 18.9 ) Pub Date : 2024-11-22 , DOI: 10.1038/s42255-024-01169-7
Mhairi Paul, Mark Nixon

Cushing’s syndrome, a condition of chronic glucocorticoid excess, disrupts metabolic homeostasis, driving fat redistribution and promoting insulin resistance. New research uses a series of elegant approaches to reveal acyl-CoA-binding protein (ACBP) as a mediator of the metabolic disturbances associated with elevated glucocorticoid levels in mice.

中文翻译:


ACBP 协调库欣综合征中的代谢表型



库欣综合征是一种慢性糖皮质激素过量的疾病,会破坏代谢稳态,推动脂肪重新分布并促进胰岛素抵抗。新研究使用一系列优雅的方法来揭示酰基辅酶 A 结合蛋白 (ACBP) 是与小鼠糖皮质激素水平升高相关的代谢紊乱的介质。
更新日期:2024-11-22
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