The number of candidates on the waiting list for heart transplantation (HT) continues to far outweigh the number of available organs, and the donor heart nonuse rate in the United States remains significantly higher than that of other regions such as Europe. Although predicting outcomes in HT remains challenging, our overall understanding of the factors that play a role in post-HT outcomes continues to grow. We observe that many donor risk factors that are deemed "high-risk" do not necessarily always adversely affect post-HT outcomes, but are in fact nuanced and interact with other donor and recipient risk factors. The field of HT continues to evolve, with ongoing development of technologies for organ preservation during transport, expansion of the practice of donation after circulatory death, and proposed changes to organ allocation policy. As such, the field must continue to refine its processes for donor selection and risk prediction in HT.

中文翻译：

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2024 年心脏移植的供体选择。


心脏移植 （HT） 等待名单上的候选者数量继续远远超过可用器官的数量，美国的供体心脏不使用率仍然明显高于欧洲等其他地区。尽管预测 HT 的结果仍然具有挑战性，但我们对在 HT 后结果中发挥作用的因素的整体理解仍在继续增长。我们观察到，许多被认为是“高风险”的供体风险因素不一定总是对 HT 后结局产生不利影响，但实际上是微妙的，并与其他供体和受体风险因素相互作用。随着运输过程中器官保存技术的不断发展，循环死亡后捐献实践的扩大以及器官分配政策的拟议变化，HT 领域不断发展。因此，该领域必须继续改进其 HT 中供体选择和风险预测的过程。