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A major step forward toward high-resolution nanopore sequencing of full-length proteins
Molecular Cell ( IF 14.5 ) Pub Date : 2024-11-21 , DOI: 10.1016/j.molcel.2024.10.038
Moon Hyeok Choi, Chirlmin Joo

In a recent publication in Nature, Motone et al.1 report the development of a protein sequencing method using nanopores that enables the reading of long protein strands. This method allows for multi-pass re-reading and can detect single amino acid substitutions as well as post-translational modifications (PTMs).

中文翻译:


向全长蛋白质的高分辨率纳米孔测序迈出重要一步



在最近发表在《自然》杂志上的一篇文章中,Motone 等人1 报道了一种使用纳米孔的蛋白质测序方法的开发,该方法能够读取长蛋白质链。该方法允许多通道重读,并且可以检测单个氨基酸替换以及翻译后修饰 (PTM)。
更新日期:2024-11-21
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