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Unraveling the tumor-initiating cells in hepatocellular carcinoma
Cancer Cell ( IF 48.8 ) Pub Date : 2024-11-21 , DOI: 10.1016/j.ccell.2024.10.018
Yu Man Tsui, Daniel Wai-Hung Ho, Irene Oi-Lin Ng

Aggressive features of hepatocellular carcinoma (HCC) are highly related to liver tumor-initiating cells (TICs), which are heterogeneous and plastic. In this issue of Cancer Cell, Yang et al. reveal the ability of CD49f-high TICs in shaping the tumor immunosuppressive microenvironment in HCC.

中文翻译:


揭示肝细胞癌中的肿瘤起始细胞



肝细胞癌 (HCC) 的侵袭性特征与肝肿瘤起始细胞 (TIC) 高度相关,后者具有异质性和可塑性。在本期 Cancer Cell 中,Yang 等人揭示了 CD49f 高 TICs 在塑造 HCC 肿瘤免疫抑制微环境方面的能力。
更新日期:2024-11-21
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